Glycans & proteoglycans : The Sweet & Smart Molecules of the 21st century

Welcome lunch

Room Charles Bagard (ED10)

Welcome reception from IAL coordinators, FR3209 BMCT Director, UMR 7365 CNRS Lorraine University Director

Amphitheater Charles Lepois

Sylvie Fournel-Gigleux, Jean-Christophe Bourdon, Didier Mainard, Jean-Yves Jouzeau, Hugues Lortat Jacob

GlycoTalk (Recorded) - Sweet-talk between pathogens and hosts

Anne Imberty (Grenoble, France)

https://lia-frbmct-2017.sciencesconf.org/data/program/Anne_Imberty.docx

Session 1: How are glycosaminoglycans & proteoglycans synthesized?

› Glycosaminoglycan and proteoglycan synthesis - Kristian Prydz, Oslo, Norway 14:15-14:45 (30min)

Presentations of “My Glycans in 300s" (Recorded)

Coffee break - Poster session

Session 2: Glycans, proteoglycans & rare genetic diseases

› Mutations in O-GlcNAc transferase and X-linked intellectual disability - Daan Van Aalten, Dundee, UK 16:00-16:30 (30min)

› Heparan sulphate in chondrocytes: Friend or Foe ? - Andrea Vortkamp, Essen, Germany 16:45-17:15 (30min)

› Insights into the complexity of Congenital Disorders of Glycosylation - François Foulquier, Lille, France 17:15-17:45 (30min)

Reception dinner

	Mer. 18	Jeu. 19
09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00	Welcome lunch 12:00 - 13:30 (1h30) Welcome lunch Room Charles Bagard (ED10) Welcome reception from IAL coordinators, FR3209 BMCT Director, UMR 7365 CNRS Lorraine University Director 13:30 - 13:45 (15min) Welcome reception from IAL coordinators, FR3209 BMCT Director, UMR 7365 CNRS Lorraine University Director Amphitheater Charles Lepois Sylvie Fournel-Gigleux, Jean-Christophe Bourdon, Didier Mainard, Jean-Yves Jouzeau, Hugues Lortat Jacob GlycoTalk (Recorded) - Sweet-talk between pathogens and hosts 13:45 - 14:15 (30min) GlycoTalk (Recorded) - Sweet-talk between pathogens and hosts Anne Imberty (Grenoble, France) https://lia-frbmct-2017.sciencesconf.org/data/program/Anne_Imberty.docx Session 1: How are glycosaminoglycans & proteoglycans synthesized? 14:15 - 15:00 (45min) Session 1: How are glycosaminoglycans & proteoglycans synthesized? › Glycosaminoglycan and proteoglycan synthesis - Kristian Prydz, Oslo, Norway 14:15-14:45 (30min) Presentations of “My Glycans in 300s" (Recorded) 15:00 - 15:30 (30min) Presentations of “My Glycans in 300s" (Recorded) Coffee break - Poster session 15:30 - 16:00 (30min) Coffee break - Poster session Session 2: Glycans, proteoglycans & rare genetic diseases 16:00 - 18:00 (2h) Session 2: Glycans, proteoglycans & rare genetic diseases › Mutations in O-GlcNAc transferase and X-linked intellectual disability - Daan Van Aalten, Dundee, UK 16:00-16:30 (30min) › Heparan sulphate in chondrocytes: Friend or Foe ? - Andrea Vortkamp, Essen, Germany 16:45-17:15 (30min) › Insights into the complexity of Congenital Disorders of Glycosylation - François Foulquier, Lille, France 17:15-17:45 (30min) Reception dinner 20:00 - 20:00 () Reception dinner	Session 3: Glycosaminoglycans, inflammation & Cancer 9:00 - 11:00 (2h) Session 3: Glycosaminoglycans, inflammation & Cancer › Heparan Sulfate proteoglycans as regulators of cancer stem cell functions - Martin Götte, Münster, Germany 09:00-09:30 (30min) › p53: a system of protein isoform orchestrating tissue regeneration in response to extracellular matrix ? - Jean-Christophe Bourdon, Dundee, UK 09:30-10:00 (30min) › Mechanistic and epigenetic aspects of hyaluronan synthesis - Alberto Passi, Varese, Italy 10:15-10:45 (30min) Coffee break - Poster session 11:00 - 11:20 (20min) Coffee break - Poster session Presentations of “My Glycans in 300s” 11:20 - 11:40 (20min) Presentations of “My Glycans in 300s” Session 4: Glycosaminoglycan-based Drugs 11:40 - 13:00 (1h20) Session 4: Glycosaminoglycan-based Drugs › Chemical biology tools to explore heparan sulfate biology and develop novel biotherapeutics - Jeremy Turnbull, Liverpool, UK 11:40-12:10 (30min) › A peptide and a GAG combine to block HIV-entry: from structure-function studies to in vivo analysis - Hugues Lortat-Jacob, Grenoble, France 12:30-13:00 (30min) Lunch 13:00 - 14:00 (1h) Lunch Session 5: Advances in Glycotechnologies Concluding Remarks & LIA Workshop Closure 14:00 - 15:30 (1h30) Session 5: Advances in Glycotechnologies › Biomimicry at the molecular level: Molecularly imprinted polymers as synthetic antibodies for bioimaging of cell surface glycans - Karsten Haupt, Compiègne, France 14:00-14:30 (30min) › Glycosaminoglycan analysis by biophotonic approaches - Stéphane Brézillon,Reims, France 14:30-15:00 (30min) 15:00 - 15:30 (30min) Concluding Remarks & LIA Workshop Closure Sylvie Fournel-Gigleux, Jean-Christophe Bourdon, Jean-Yves Jouzeau