Glycans & proteoglycans : The Sweet & Smart Molecules of the 21st century

Session 3: Glycosaminoglycans, inflammation & Cancer

› Heparan Sulfate proteoglycans as regulators of cancer stem cell functions - Martin Götte, Münster, Germany 09:00-09:30 (30min)

› p53: a system of protein isoform orchestrating tissue regeneration in response to extracellular matrix ? - Jean-Christophe Bourdon, Dundee, UK 09:30-10:00 (30min)

› Mechanistic and epigenetic aspects of hyaluronan synthesis - Alberto Passi, Varese, Italy 10:15-10:45 (30min)

Coffee break - Poster session

Presentations of “My Glycans in 300s”

Session 4: Glycosaminoglycan-based Drugs

› Chemical biology tools to explore heparan sulfate biology and develop novel biotherapeutics - Jeremy Turnbull, Liverpool, UK 11:40-12:10 (30min)

› A peptide and a GAG combine to block HIV-entry: from structure-function studies to in vivo analysis - Hugues Lortat-Jacob, Grenoble, France 12:30-13:00 (30min)

Lunch

Session 5: Advances in Glycotechnologies

› Biomimicry at the molecular level: Molecularly imprinted polymers as synthetic antibodies for bioimaging of cell surface glycans - Karsten Haupt, Compiègne, France 14:00-14:30 (30min)

› Glycosaminoglycan analysis by biophotonic approaches - Stéphane Brézillon,Reims, France 14:30-15:00 (30min)

Concluding Remarks & LIA Workshop Closure

Sylvie Fournel-Gigleux, Jean-Christophe Bourdon, Jean-Yves Jouzeau